Capecitabine (Xeloda®) Breast and colon cancer Dasatinib (Sprycel®) Chronic myeloid leukemia/acute lymphocytic leukemia Erlotinib (Tarceva®) Non-small cell lung cancer and pancreatic cancer Gefitinib (Iressa®) Non-small cell lung cancer Imatinib (Gleevec®) Chronic myeloid leukemia/gastro-intestinal stromal tumor
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چکیده
In BrIef Non-adherence can have profound clinical consequences in the treatment of chronic diseases— especially cancer. Medication non-adherence in patients with cancer is a growing concern today due to the increasing availability of new oral agents. Many factors contribute to patient non-adherence to treatment regimens. Understanding the potential barriers and factors that affect patient adherence will help providers develop strategies to promote patient adherence to oral treatment regimens. Optimal patient outcomes require adherence, education, communication, ongoing monitoring, and follow-up.
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Evaluation of the Effect of Curcumin and Imatinib on BCR-ABL Expression Gene in Chronic Human k562 Cells
Background and Aims: Detection of overexpression in tumor-inhibiting genes provides valuable information for leukemia diagnosis and prognosis. Chronic myeloid leukemia (CML) is a stem cell disorder determined by a well-defined genetic anomaly involving BCR-ABL translocation in the Philadelphia chromosome. Curcumin is a chemo-preventive agent for the primary cancer targets, such as the breast, p...
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Background: Solid tumors may occur in 3% of the patients with chronic myeloid leukemia (CML). In this paper, we presented a case of CML following treatment of colon cancer. Case Presentation: A 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. Following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...
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PURPOSE On June 28, 2006, the U.S. Food and Drug Administration approved dasatinib (Sprycel; Bristol-Myers Squibb), a new small-molecule inhibitor of multiple tyrosine kinases, for the treatment of adults with chronic phase, accelerated phase, or myeloid or lymphoid blast phase chronic myeloid leukemia (CML) or Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+) ALL) with resis...
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